Hope Through Innovation
Understanding Complex Regional Pain Syndrome (CRPS): Hope Through Innovation
Complex Regional Pain Syndrome (CRPS) is a chronic neurological condition that primarily affects the arms, legs, hands, or feet. It can cause debilitating pain, swelling, changes in skin color and texture, muscle spasms, and even atrophy. While the exact mechanisms of CRPS are not fully understood, it is generally associated with dysfunction in the central or peripheral nervous system. In more than 90% of cases, CRPS is triggered by nerve trauma resulting from an injury, fracture, or surgery.
CRPS can be extremely difficult to diagnose due to the wide range of symptoms, and if left untreated, it may progress to more severe and disabling stages. However, early recognition and innovative treatment options can provide significant relief and help improve quality of life.
Stages of CRPS
CRPS typically progresses through three stages:
Stage 1 (1-3 Months):
- Severe burning or aching pain
- Muscle spasms and joint pain
- Increased swelling
- Changes in skin color, appearance, and texture
Stage 2 (3-6 Months):
- Increasing pain
- Stiff joints and muscle weakness
- Worsening skin abnormalities
Stage 3 (6+ Months, Untreated):
- Severe, debilitating pain
- Muscle and tendon atrophy
- Muscle contractures, making movement extremely difficult
Innovative Treatment with the neoGEN® System
The neoGEN® Electric Cell-Signaling Treatment (EcST) device offers a revolutionary, non-invasive approach to managing CRPS symptoms. This advanced technology is FDA-cleared for indications that address many of the challenges CRPS patients face, making it a versatile and effective treatment option. For individuals dealing with post-traumatic pain syndromes or chronic, long-term intractable pain, the neoGEN System provides symptomatic relief by improving local blood circulation and relaxing tight muscles. These therapeutic effects also help reduce swelling, ease muscle spasms, and restore function to areas impacted by nerve trauma. By re-educating neuromuscular pathways and preventing disuse atrophy, the neoGEN System aids in maintaining muscle strength and mobility, even in cases where pain or immobility has led to prolonged inactivity. With its ability to support recovery naturally and non-invasively, the neoGEN System offers hope for patients seeking lasting relief and improved quality of life.
A Brighter Future for CRPS Patients
CRPS can feel overwhelming, but hope is within reach. The neoGEN® System offers a proven, innovative approach to managing the pain and challenges associated with this condition. By addressing key aspects of recovery—such as pain management, circulation improvement, and muscle rehabilitation—this technology is transforming lives.
If you are a patient struggling with CRPS or a healthcare provider seeking cutting-edge solutions for your practice, the neoGEN® System provides a safe, non-invasive option to enhance care and outcomes.
A Life-Changing Testimonial
2021: “I just wanted to say thank you for this machine! It’s changing my life! I was diagnosed with CRPS after a failed surgery in June 2020, and was left with minimal options and told I would suffer with this the rest of my life. I was defeated, depressed, and giving up hope. After multiple failed attempts with pain management doctors, their last resort was a DRG implant. I refused to do it. I searched endlessly for days to find an alternative, natural way to try to heal my damaged nerves and finally found a facility that offers treatments with Sanexas. I’m 2 weeks in on an 8-week program, and my nerve pain has diminished about 60%. I have hope for the first time in a while now. I wish I could tell the world of the differences that just 2 weeks have shown… THANK YOU isn’t enough!” — T.T.
2024:
“I can tell you that since my treatments, I’ve not had but maybe 1 or 2 small flare-ups, which are much more tolerable than what I was going through when it all began! Being a delivery driver, being on my feet is a must. Feeling my foot is essential. Having CRPS in my foot was devastating news. Pain doctors only wanted to put an implant in my back to block the sensations, which wasn’t a viable option for me. After much research, finding Sanexas literally saved my life! I’ve been running my usual 8 to 10 miles a day without issue. I can’t imagine what life would be like had I not discovered and tried the treatment!”
— T.T.
References
- S. Food and Drug Administration. “Summary of Indications for Use: neoGEN® System.”
- National Institute of Neurological Disorders and Stroke (NINDS). “Complex Regional Pain Syndrome Fact Sheet.”
- Clinical studies and patient-reported outcomes on Electric Cell-Signaling Treatment (EcST).

